Nithin Chalapathi, Theo Sternlieb, Ethan Han, Sonya M Hanson, Pilar Cossio, Aditi S Krishnapriyan, Ritwik Gupta
EMber is a self-supervised foundation model for cryo-EM that learns transferable representations of molecular structure, achieving state-of-the-art performance on conformational analysis, population estimation, and 3D reconstruction.